Skip to main content
. Author manuscript; available in PMC: 2009 Oct 15.
Published in final edited form as: Free Radic Biol Med. 2008 Jul 27;45(8):1178–1189. doi: 10.1016/j.freeradbiomed.2008.07.015

Fig. 6.

Fig. 6

Decreasing Prx II decreases intracellular glutathione and glutathione reductase activity. Alterations in intracellular levels of reduced (GSH) glutathione were determined in 36B10 and C6 glioma cell lines (A–B respectively). Intracellular GSSG was not detectable in 36B10 glioma cells. A decrease in GR activity was detected in C6 shPrx 2.3 (C) and 36B10 shPrx2.2 (D) when compared to their respective controls. Significance was determined using the student’s t-test where p < 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***).