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. Author manuscript; available in PMC: 2009 Jan 20.
Published in final edited form as: Magn Reson Med. 2008 Apr;59(4):855–865. doi: 10.1002/mrm.21573

FIG. 1.

FIG. 1

Dependence of image quality and signal to noise ratio (SNR) on TE with 9.4-T BOLD 3D microscopy (fraction of inspired oxygen = 30%). a and b: Images of one representative animal with TE = 10 ms (a) and 20 ms (b) after minimum-intensity projection of 1-mm thick coronal slabs from the 3D datasets (systemic arterial oxygen saturation level = 99%). CC = corpus callosum; IC = internal capsule. c and d: SNR values plotted as a function of TE for all studies (N = 6), where each line represents data from an individual animal; filled triangles represent data from a and b. Image insets are single-pixel thick (59 μm) coronal reconstructions (TE = 20 ms) from one study, where the signal spatial extent considered for each measurement is illustrated in two dimensions by the squares. The actual volumes for the signal measurement are 7 × 7 × 7 mm3 (c) and 1.2 × 1.2 × 0.059 mm3 (d), and the volume for noise measurement is 1.2 × 1.2 × 1.2 mm3 (not shown). SNR is statistically highest for both regions of signal measurement when TE = 20 ms; * p < 0.05.