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Expression of TCF factors in type II diabetes. TCF7L2 (red in (a)–(d)) and TCF3 (red in (f)–(i)) are absent from islets of nondiabetic individuals (a), (b), (f), and (g), but are present in islets from type II diabetics (c), (d), (h), and (i). Islets are identified by insulin (green in (b), (d), (g), and (i)). Quantitation of TCF7L2 (e) and TCF3 (j) expressions in nondiabetic (n = 4) and type II (n = 7) islets: error bars = mean +/− s.e.m. *P < .05. Scale bars = 50 μm.
