Effects of RE, I3C and their combination on the metabolism of SK-OV-3 cells with alamarBlue dye. Cells were treated over a 6 day period and alamarBlue assay was performed daily as described under methods. The data is expressed as percent of growth ± SEM, as compared to vehicle control (100%), unless noted otherwise. Level of significance is denoted as follows: *, p <0.05; **, p<0.01; ***, p<0.001. Note a synergistic action of the two agents when used in combination in contrast to each one alone.