Table 3.
ANA pattern | Antigen | Associated diseases |
Speckled | ENA, RNP, Sm, SSA/Ro, SSB/La, Scl-70, Jo-1, ribosomal-P | SLE, Mixed CTD, SS, Primary Sjogren's syndrome, PM |
Homogenous | dsDNA, Histones | SLE, Drug induced SLE |
Peripheral (rim) | RNP, Sm, SSA/Ro | SLE, SS |
Nucleolar | Anti-PM-Scl, anti-RNA polymerase I-III, anti-U3-RNP, To RNP | SS, PM |
Centromere | CENP A-E | Limited SS |