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. 2008 Dec 16;3:52. doi: 10.1186/1745-6150-3-52

Figure 1.

Figure 1

Context effects are detected using TF when none exist. Sequences were simulated under a nucleotide GTR model with π (A) + π (T) ≈ 0.6. A single dinucleotide parameter for CG NN was added to the TFnuGTR and NFnuGTR dinucleotide baseline models. The red vertical line represents the expected value under the null hypothesis (the parameter has no effect). x-axis is the MLE of CG NN, y-axis is the number of simulated alignments.