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Predicted rates of cognitive change based on baseline characterization of WMH severity. For graphical presentation, the baseline Scheltens Scale score is presented as a dichotomous variable based on the median split of the entire sample (median = 3.0). Note that higher “High WMH” refers to more severe WMH. The results from the GEE analysis suggest that the greater the more severe the baseline WMH, the greater the rate of cognitive decline.
