Table 2.
The effects of blocking sGC signaling in antennal lobe neurons
Neuron ID | Morphology | Physiology | Drug | Resting activity | Δg | Odor response | sGCir |
---|---|---|---|---|---|---|---|
PN24 | MGC-PN | ODQ | Bursts | ↓ | ↓ C ; ↑ Bl | No | |
PN25 | AC-PN | ODQ | Bursts | ↓ | X: H; ↓ M; ↑ Bl; | Yes | |
PN5 | AC-PN | ODQa | Bursts | Yes | |||
PN26 | AC-PN | ODQ | Increase | ↓ | X: M; ↓ Bl; ↑ L | No | |
PN12 | PN | ODQa | Increase | ↔ | |||
PN27 | MGC-PN | ODQ | Decrease | ↓ | X: C; ↓ Bl, B | Yes | |
PN4 | MGC-PN | ODQa,b | Decrease | ↓ | ↓ Bl, C; ↑ B | No | |
LN28 | Ib-LN | ODQ | Burst | ↔ | ↓ Bl, M; ↑ O | Yes | |
LN29 | Ib-LN | ODQ | Increase | ↓ | No | ||
LN30 | LC CB | LN | ODQ | Increase | ↔ | X: H | Yes |
LN31 | Ib-LN | ODQ | Decrease | ↓ | Yes | ||
LN32 | Ib-LN | ODQ | No change | ↔ | ↑ Bl | No | |
LN33 | Ia-LN | ODQ | No change | ↔ | No | ||
LN34 | Ib-LN | ODQ | No change | Yes | |||
TOTALS | 13 | 2 | 14 | B: 4; I: 4; D: 3; N: 3 | 12 | X: 4; ↓: 6; ↑: 6 | 7/13 ir |
Morphological and physiological categorization and all other abbreviations are defined in the Table 1 legend. LN30 was filled with LY dye and had a cell body in the LC. It was also characterized physiologically as a LN
Indicates 7NI was also applied (see Table 1)
Note the difference in resting activity observed in PN4 when 7NI was applied