FIGURE 7.

A, Palladin knock-out APSCs show increased adhesion on substrates. APSCs were cultured on purified matrix fibronectin and gelatin for 30 min. B, phase-contrast micrographs show the migration of APSCs in a wound assay. Images were taken at 0 and 24 h after scratching. C, quantification of migration data. Width = diameter of the scratch. D, proliferation of WT and Palladin null APSCs. Cells were cultured on 24-well plates. Cells were trypsinized and counted each day over 7 days. There is no difference in cell numbers in WT and Palladin knock-out cells.