Cumulated pathway regulation intersections between gained and lost
pathways between theoretical and actual co-stimulations. A and
B represent Venn diagrams for PAGE pathways gained selectively in the
actual co-stimulation paradigms compared with the theoretical composites
cumulated over the three experimental time points (2, 4, and 8 h). A
depicts pathways gained and up-regulated, and B depicts pathways
gained and down-regulated. C and D represent Venn diagrams
for PAGE pathways lost selectively from the theoretical composite results to
the actual co-stimulations cumulated over the three experimental time points
(2, 4, and 8 h). C depicts pathways lost and up-regulated, and
D depicts pathways lost and down-regulated.