Table 1.
Summary of physiologic parameters before (preischemia) and during (ischemia) 90 min of middle cerebral artery occlusion in male and female rhesus macaques
| Heart rate (beats per minute) | Systolic BP (mm Hg) | Diastolic BP (mm Hg) | Respiratory rate (breaths per minute) | EtCO2 (mm Hg) | Rectal temperature (°C) | Glucose (mg/dl) | |
| Male macaques | |||||||
| Preischemia | 120 ± 2 (n = 26) | 74 ± 3 (n = 20) | 48 ± 2 (n = 20) | 17 ± 1 (n = 26) | 32 ± 2 (n = 26) | 35.5 ± 0.1 (n = 25) | 53 ± 6 (n = 4) |
| Ischemia | 115 ± 2 (n = 22) | 93 ± 3 (n = 22)a | 60 ± 1 (n = 22)a | 15 ± 1 (n = 19) | 27 ± 1 (n = 22)a | 36.5 ± 0.2 (n = 22)a | 69 ± 2 (n = 5)a |
| Female macaques | |||||||
| Preischemia | 122 ± 4 (n = 25) | 81 ± 5 (n = 17) | 55 ± 2 (n = 17)b | 16 ± 1 (n = 23) | 32 ± 2 (n = 25) | 35.9 ± 0.3 (n = 24) | 62 ± 5 (n = 5) |
| Ischemia | 116 ± 2 (n = 19) | 92 ± 6 (n = 19) | 59 ± 2 (n = 19) | 12 ± 0 (n = 19)ab | 25 ± 1 (n = 19)a | 37.0 ± 0.2 (n = 19)a | 64 ± 2 (n = 8) |
n, total number of measurements made from 3 animals within an experimental group during a specific time interval
a
P < 0.05 compared with preischemia within an experimental group
b
P < 0.05 compared with males within a time interval