Fig. 1.
Effect of GHRH and JMR-132 on the proliferation rate of LNCaP cancer cells, measured after an incubation of 72 h. (A) Changes in proliferation rate of LNCaP prostate cancer cells after exposure to GHRH antagonist JMR-132 and GHRH (1-29)NH2. Percentage increase or decrease are expressed vs. LNCaP cells cultured in the absence of JMR-132 or GHRH (1-29)NH2. *P < 0.05; **P < 0.005. (B) Western blot analysis of expression of PCNA in LNCaP prostate cancer cells after exposure to GHRH antagonist JMR-132 and GHRH(1-29)NH2; n = 2