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. 2008 Dec 15;105(51):20470–20475. doi: 10.1073/pnas.0811209106

Fig. 5.

Fig. 5.

Effects of GHRH and JMR-132 on protein and lipid oxidation markers and on generation of ROS in LNCaP prostate cancer cells. (A) Detection of expression of oxidation markers (nitrotyrosine and MDA) in LNCaP prostate cancer cells after incubation for 72 h with GHRH antagonist JMR-132 and GHRH(1-29)NH2; n = 2. (B) Detection of expression of the carbonyl groups in LNCaP prostate cancer cells after 72-h treatment with GHRH antagonist JMR-132 and GHRH(1-29)NH2; n = 2. (C) Changes in generation of ROS after 30-min incubation. Percentage increase or decrease are expressed vs. LNCaP cells cultured in the absence of JMR-132 or GHRH (1-29)NH2. ***, P < 0.005.