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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Gastroenterology. 2008 Jul 16;135(4):1142–1154. doi: 10.1053/j.gastro.2008.07.009

Figure 3. Relationship between 12-Week Post-treatment Body Weight and Sibutramine Dose Based on Gene Combinations.

Figure 3

P-values indicate overall treatment effects for specific genotype combination. Least squares (adjusted for baseline weight and other covariates) means ± SE are plotted, unadjusted p-values from ITT analyses based on ANCOVA models. N refers to number of patients with complete data in each group. There were significant effects of sibutramine on post treatment weight in patients with the specified genetic combination indicated.