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. Author manuscript; available in PMC: 2009 Nov 1.

Published in final edited form as: Mech Ageing Dev. 2008 Sep 19;129(11):649–655. doi: 10.1016/j.mad.2008.09.002

Fig. 4 — (A) Immunofluorescence staining demonstrating a dramatic increase in expression of BACE1 (green) in the CA1 region of the hippocampus and adjacent cortex in sections from a cholesterol-fed rabbit brain compared to section from a control rabbit. DAPI (blue) was used as nuclear counterstain. Bar= 20μm.

(B) Immunostaining for RAGE is low in sections from CA1 region of hippocampus or adjacent cortex in a control rabbit. In section from CA1 and adjacent cortex from a cholesterol-fed rabbit, immunoreactivity to RAGE (green) is increased in hippocampus and in cortex. Nuclei were stained with DAPI (blue). Bar= 20μm

Fig. 4 — (A) Immunofluorescence staining demonstrating a dramatic increase in expression of BACE1 (green) in the CA1 region of the hippocampus and adjacent cortex in sections from a cholesterol-fed rabbit brain compared to section from a control rabbit. DAPI (blue) was used as nuclear counterstain. Bar= 20μm.

(B) Immunostaining for RAGE is low in sections from CA1 region of hippocampus or adjacent cortex in a control rabbit. In section from CA1 and adjacent cortex from a cholesterol-fed rabbit, immunoreactivity to RAGE (green) is increased in hippocampus and in cortex. Nuclei were stained with DAPI (blue). Bar= 20μm