Skip to main content
. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2008 Nov 12;79(3-5):157–163. doi: 10.1016/j.plefa.2008.09.012

Figure 2.

Figure 2

Biosynthesis of specialized mediators in resolution of acute inflammation. Local mediators include the lipoxins (LX) derived from arachidonic acid (AA); resolvins derived from omega-3 PUFAs eicosapentaenoic acid (EPA; resolvins E series) and docosahexaenoic acid (DHA; resolvins D series); and protectins enzymatically derived from DHA. The structures of each of these key mediators have been confirmed by total organic synthesis (see text for details).