Table 1.
Morphometric measurements, food intake and food efficiency ratio (FER) in all groups
Parameters | 2 weeks | 4 weeks | ||
Rapamycin, N = 6 | Control, N = 6 | Rapamycin, N = 7 | Control, N = 7 | |
Change in body weighta (grams) | 63 ± 6d, e | 73 ± 8d | 128 ± 7f | 159 ± 11 |
Change in body lengtha (centimeters) | 7.6 ± 0.6d, e | 8.6 ± 0.5d | 13 ± 1.2f | 16 ± 0.7 |
Tibial Lengthb (centimeters) | 3.0 ± 0.05d, e | 3.2 ± 0.05d | 3.4 ± 0.09f | 3.7 ± 0.15 |
Total food intakeb (grams) | 185 ± 1.8 | 183 ± 5.3 | 390 ± 32 | 410 ± 4.8 |
Food Efficiency Ratioc (FER) | 3.0 ± 0.5e | 2.6 ± 0.6 | 3.0 ± 0.5f | 2.6 ± 0.3 |
aDifference between measurements at 2 or 4 weeks and baseline
bObtained at the time of sacrifice
cTotal food consumed/weight gain during the study period
dp < 0.0001, 2 weeks versus 4 weeks (same group)
ep < 0.001, rapamycin versus control at 2 weeks
fp < 0.0001, rapamycin versus control at 4 weeks