Table 3.

Correlations of demographic and Alcohol use variables with WMSH volumes in LTAA.

	Pearson Correlation Coefficients
	Periventricular WMSH		Deep WMSH		Age
	r	p	R	p	r	p
Correlations
Age	0.401**	0.004	0.449*	0.001	1.000
Lifetime Alcohol Dose	0.335*	0.016	0.336*	0.016	0.332*	0.017
Lifetime Alcohol Use	0.480***	<0.001	0.436**	0.001	0.418*	0.002
Peak Alcohol Dose	0.338*	0.015	0.370**	0.008	0.302*	0.031
Peak Alcohol Use	0.577***	<0.001	0.473***	<0.001	0.384*	0.005
Length of Abstinence	−0.073	0.610	0.004	0.980	0.315*	0.024
Family Drinking Density	−0.079	0.583	−0.098	0.494	0.035	0.806
Years of Education	0.036	0.800	−0.011	0.940	−0.161	0.258
Partial Correlations, Controlling for Age
Lifetime Alcohol Dose	0.234	0.102	0.223	0.122
Lifetime Alcohol Use	0.376**	0.007	0.306*	0.031
Peak Alcohol Dose	0.248	0.083	0.276	0.053
Peak Alcohol Use	0.500***	<0.001	0.364**	0.009
Length of Abstinence	−0.229	0.109	−0.162	0.262
Family Drinking Density	−0.101	0.483	−0.127	0.377
Years of Education	0.112	0.440	0.070	0.630
Partial Correlations, Controlling for Lifetime Alcohol Use
Age	0.251	0.079	0.326*	0.021

The Periventricular and Deep WMSH volumes are adjusted for inter-subject differences in total cerebral white matter volume.

Alcohol use measures represent the quantiy of alcohol consumed during a given time frame.

Alcohol dose measures represent the average monthly intake of alcohol during a given time frame.

Family drinking density is the proportion of first-degree relatives who were problem drinkers.