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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Dev Neurobiol. 2009 Feb 1;69(2-3):88–104. doi: 10.1002/dneu.20693

Figure 6.

Figure 6

Reduction in progenitor pool and increase in cell death in retinas infected with RCAS-ash1. A–D: Double-labeling of E8 retinas infected with RCAS-GFP (A, B) or RCAS-ash1 (C, D) for viral protein p27 to identify infected regions (A, C) and for BrdU incorporation (B, D). E–H: Double-labeling of E8 retinas infected with RCAS-GFP (E, F) or RCAS-ash1 (G, H) for viral protein p27 (E, G) and for ngn2 mRNA with in situ hybridization (F, H). I–L: Double-labeling of E10 retinas infected with RCAS-GFP (I, J) or RCAS-ash1 (K, L) for viral protein p27 (I, K) and for cell death with TUNEL assay (J, L). Infected regions are indicated by lines. Scale bars: 100 μm.