Table 1.

Most common adverse effects with combination therapy

Adverse effect	Nr of studies	Nr of patients	OR; 95% CI
Pneumonia	7	5229	OR 1.80; 95% CI 1.48–2.18
Candidiasis	6	1958	OR 5.73; 95% CI 3.07–10.67
Hoarseness	2	585	OR 8.79; 95% CI 1.11–69.62
Nasopharyngitis	2	3535	OR 1.28; 95% CI 1.05–1.56
URTI	5	4963	OR 1.23; 95% CI 1.04–1.47

Abbreviations: CI, confidence interval; OR, odds ratio; URTI, upper respiratory tract infections.