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. 2008 Sep;3(3):477–481. doi: 10.2147/copd.s2837

Figure 2.

Figure 2

(Upper) Animals receiving ET-1 prior to cigarette smoke (CS) exposure had a significantly higher percentage of BALF neutrophils than controls treated only with cigarette smoke or ET-1 and room air (RA). The effect of ET-1 was reversed by pretreatment with HJP272 (N = 3 for all groups). (Lower) Animals receiving ET-1 or ET-1 plus HJP272 prior to CS had fewer total BALF leukocytes than controls treated with cigarette smoke alone, but the differences among these 3 treatment groups were not statistically significant (N = 3 for all groups). For both graphs, T-bars indicate SEM.