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. 2008 Sep;3(3):443–452. doi: 10.2147/copd.s2588

Table 2.

Peak and submaximal exercise response, muscle function, and body composition

	GOLD 2		GOLD 3
	Mean	SD	Mean	SD	p-value
Wmax, W^~	91.0	± 30.7	74.2	± 26.7	p<0.001
Vo₂ peak, mL/min^~	1472.8	± 354.4	1353.2	± 304	p<0.05
Vo₂ peak/weight, mL/kg/min^~	19.2	± 3.9	18.1	± 4	n.s
Vco₂ peak, mL/min^~	1535.9	± 407.4	1329.8	± 345.6	p<0.05
Vco₂ peak/weight, mL/kg/min^~	20	± 4.8	17.7	± 4.6	p<0.05
RQ peak^~	1.04	± 0.1	0.98	± 0.1	p<0.05
PAO2 peak mm Hg^~	78.2	± 14.5	64.1	± 14.4	p<0.001
PaACO2 peak mmHg^{^}	40.2	± 4.9	44.6	± 6.6	p<0.001
Ve peak, l/min^~	56.1	± 15.3	47	± 12.5	p<0.001
Ve reserve, %^~	16.1	± 16	0	± 20.2	p<0.001
HR peak, beats/min^~	130.6	± 19.6	130.7	± 18	n.s.
HR reserve, %^~	14.5	± 11.4	15.4	± 10.9	n.s.
6 MWD, m ^~	525.9	± 84.9	504.0	± 102.6	n.s.
CWR-70%, min ^{^}	14.46	± 12.33	11.53	± 8.53	n.s.
Quadr force Nm. ^~	151.8	± 47.9	160.1	± 44.9	n.s.
Quadr force perc. pred ^~	93.5	± 22.2	90.1	± 20	n.s.
Quadr av. power −60° (Watt) ^~	61.8	± 22	65.6	± 22	n.s.
Quadr av. power −180° (Watt) ^~	104.4	± 36.5	110	± 38.1	n.s.
Handgrip force % pred ^~	77.7	± 18.8	81.5	± 14.7	n.s.
Pi-max % pred ^~	67,1	± 22.5	63.4	± 17.8	n.s.
Pe-max % pred ^~	51.6	± 18.9	48.8	± 15.7	n.s.
BMI (kg/m²) ^~	27	± 4.4	25.9	± 4.4	n.s.
FFMI male (kg/m²) ^~	17.8	± 1.7	17	± 1.5	0.01
FFMI female (kg/m²) ^~	16.9	± 2.2	16.3	± 2.2	n.s.
Depletion FFM, n, (%)^‡	19(15%)		11 (21%)		n.s.
Nutritional depletion, n (%)^‡	20(16%)		12 (23%)		n.s.
FM % weight male ^~	32	± 5	32	± 6	n.s.
FM % weight female ^~	41	± 6	44	± 5	n.s.
Invol. Weight loss n	2 (2%)		0

Notes: Data are presented as mean ± SD unless otherwise indicated.

^~

Independent Samples T-Test for continuous variables with normal distribution;

^{^}

a nonparametric Mann Whitney U-Test;

^‡

Chi-Squared Test for categorical variables.

Abbreviations: