Effect of NIV on HCVR Mean (SEM) HCVR at D0, D5 and 3M is shown. There was no overall significant increase in HCVR (p = 0.23), however there was a significant increase in HCVR from baseline to 5D when NIV use was good (p = 0.009).
Abbreviations: HCVR, hypercapnic ventilatory response; NIV, noninvasive ventilation; SEM, standard error of mean.