Figure 3.
Reduced incidence and SK lesion in the CD3F(ab′)2-treated mice compared to untreated controls. (A) The bar diagram demonstrates the percentage severity of both Balb/s and C57Bl/6 mice at day 18 p.i. The treated animals show reduced incidence of SK compared to untreated animals. (C, D) The line diagrams denote the mean SK and angiogenesis lesion scores, respectively, in CD3F(ab′)2-treated and untreated C57Bl/6 mice infected with 5 × 105 pfu HSV-1RE at different time points p.i. (E, F) The line diagrams denote the mean SK and angiogenesis lesion scores, respectively, in CD3F(ab′)2-treated and untreated Balb/c mice infected with 5 × 105 pfu HSV-1RE at different time points p.i. *Statistically significant differences compared to untreated control (P ≤ 0.05).