Table 2.

MFI of intracellular signaling molecules in myeloid cells from C-fms-rtTA/(TetO)₇-CMV-Api6 bitransgenic mice

		pStat3		pErk		pP38
		−DOX	+DOX	−DOX	+DOX	−DOX	+DOX
	CD11b	23.81±3.74	25.4±3.93	19.94±3.08	18.16±1.85	18.64±2.6	28.77±6.53*
Bone Marrow	CD11c	20.41±6.93	22.91±10.52	31.57±7.86	31.17±5.25	18.30±3.51	20.04±3.29
	GR-1	25.23±4.07	26.54±1.34	20.09±1.97	24.7±1.1	19.23±4.73	23.76±5.87
	CD11b	23.91±7.69	80.81±23.06*	21.83±7.22	154.59±80.23*	25.12±1.86	158.36±79.83*
PBMC	CD11c	21.39±3.73	28.99±7.31	27.76±6.24	28.24±7.34	30.68±10.53	34.85±12.19
	GR-1	23.82±6.46	44.88±12.95*	28.77±7.86	132.92±83.79*	22.01±1.65	32.67±12.16*
	CD11b	21.29±4.95	37.84±9.36*	26.47±3.59	120.09±53.15*	36.21±5.77	142.98±67.28*
Lung	CD11c	18.67±4.05	24.51±6.21	32.21±8.31	36.59±11.04	21.71±3.76	27.26±11.76
	GR-1	22.82±4.42	38.46±14.97*	25.95±5.93	132.67±67.90*	22.32±4.15	43.65±22.57*

Comparison of the mean fluorescence intensity (MFI) of pStat3, pErk and pP38 in CD11b+, CD11c+ and GR-1+ cell populations obtained from the bone marrow, PBMC and Lung. The data are mean value ± SD from three independent experiments.

^**, P< 0.05.