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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Future Virol. 2008 Nov;3(6):553–566. doi: 10.2217/17460794.3.6.553

Figure 1. Lethal mutagenesis as an antiviral strategy against RNA viruses.

Figure 1

Treatment with a nucleoside mutagen (µ) increases the number of mutations per genome, decreasing the fitness of the progeny viral population. µMP, µDP and µTP represent mono-, di- and triphosphorylated forms of the nucleoside, respectively. RdRp: RNA-dependent RNA polymerase.