Table 2.
VAX004: Summary of the posterior distributions of the transmission probability and the vaccine efficacy per infectious sexual contact for the overall study population and by baseline risk level, compared to the standard analysis
p | VE (Bayesian) | VE (Coxa) | ||||||
---|---|---|---|---|---|---|---|---|
Risk level | Totalb | Infected | Median | 95% C.S. | Median | 95% C.S. | Estimate | 95% C.I. |
Overall | 8772 | 368 | 0.0056 | 0.0044, 0.0071 | 0.069 | -0.15, 0.26 | 0.06 | -0.17, 0.24 |
Low | 3605 | 57 | 0.0020 | 0.0010, 0.0036 | -0.23 | -1.48, 0.35 | -0.48 | -1.93, 0.26 |
Middle | 4546 | 229 | 0.0054 | 0.0041, 0.0071 | 0.02 | -0.28, 0.25 | 0.03 | -0.25, 0.25 |
High | 621 | 82 | 0.020 | 0.013, 0.030 | 0.56 | 0.22, 0.75 | 0.43 | 0.04, 0.66 |
Results based on Cox proportional hazards model in Gurwith et al. (2005).
Total number of six-month intervals.