Fig. 2.

Weights of male and female guinea pigs at PND5–10, PND35–45, and PND120–150 measured at 2 h before their challenge with VX, soman, or sarin. Guinea pigs were weighed at 2 h before the subcutaneous injection of any given dose of VX, soman, or sarin. In each graph, bar graphs, and error bars represent mean and S.D. of weights from all animals that were exposed to the nerve agents. Number of animals in each experimental group ranged from 36 to 80. The weight of the guinea pigs increased with their age, and, in adulthood, the weight of males was significantly higher than that of females (***, P < 0.001 according to one-way ANOVA followed by Tukey post hoc test for multiple comparisons).