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. Author manuscript; available in PMC: 2009 Jul 7.
Published in final edited form as: Cell Metab. 2009 Jan 7;9(1):64–76. doi: 10.1016/j.cmet.2008.10.010

Figure 6. No effect of orexin overexpression on the weight gain of ob/ob mouse.

Figure 6

(A) The body weight growth of ob/ob; CAG/orexin male mice was similar to that of ob/ob male mice (p=0.76).

(B) Fat mass of 28 week-old ob/ob male mice with or without CAG/orexin transgene. There is no significant difference in fat mass for both male and female. 13–20 mice per group.

(C) The body weight growth of OX2R agonist-infused ob/ob mice was similar to that of vehicle-injected ob/ob mice maintained on a low fat (C) and a high fat diet. Data are expressed as means ± SEM.