Table 4.
Effect of IL-1 Ra on cumulative concentration-response curves for MCh in cultured tracheal smooth muscle after in vitro ozone exposure.
| Control
|
Ozone
|
|||
|---|---|---|---|---|
| EC50 (M) | Tmax | EC50 (M) | Tmax | |
| MCh | ||||
| Saline (95% CI) | 1.91 ×10−6 (1.24 ~ 2.58) | 105.5±11.2 | 3.81×10−7* (1.97 ~5.65) | 113.4±10.9 |
| IL-1 Ra (95% CI) | 2.63 ×10−6 (1.86~3.40) | 109.2±10.3 | 1.65×10−6 (1.14~2.167) | 119.2±12.4 |
EC50 values are given in molar concentration with 95% confidence interval (95% CI) in parentheses.
N=5.
*
Significant difference between air and ozone exposure; p≤ 0.05.