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. Author manuscript; available in PMC: 2009 Dec 25.
Published in final edited form as: J Med Chem. 2008 Dec 25;51(24):8000–8011. doi: 10.1021/jm8011257

Figure 6.

Figure 6

Ki versus nitrogen atom in para, meta and ortho position toward linkage of nine different groups of compounds indicate that in general the order of tightness of binding is para>meta>ortho (Table 1).