Table 7.
Summary of previously reported isoflavone concentrations in infants.
| Author | Fluid Measured | n | Age | Genistein (ng/ml) | Daidzein (ng/ml) | Equol (ng/ml) |
|---|---|---|---|---|---|---|
| Soy-formula-fed infants | ||||||
| Setchell et al. (1997) | Plasma | 7 | 4 mo | 684±443 | 295±59.5 | 2.0 |
| Venkataraman et al. (1992) | Urine | 8 | 2 mo | 26,451±8559 | 25,399±8081 | 6.4±6.4 |
| 7 | 4 mo | 8758±3808 | 17,577±5452 | 1.5±1.5 | ||
| Franke et al. (2006) | Plasma | 3 | 9-24 mo | 276±106† | - | |
| Irvine et al. (1998) | Urine | 4 | 2-16 wk | No direct values | ||
| SEAD study | Urine | 125 | 0-12 mo | 5891×/÷3.1 | 5097×/÷2.5 | 2.3×/÷4.6 |
| Saliva | 119 | 0-12 mo | 11.6×/÷5.1 | 5.2×/÷5.8 | - | |
| Whole Blood | 27 | 0-12 mo | 757×/÷3.0 | 256×/÷2.8 | - | |
| Cow-milk-formula-fed infants | ||||||
| Setchell et al. (1997) | Plasma | 7 | 4 mo | 3.2±0.7 | 2.1±0.3 | 4.1±0.5 |
| Venkataraman et al. (1992) | Urine | 5 | 2 mo | 205±52 | 155±64 | 42.6±2.3 |
| 6 | 4 mo | 536±393 | 706±555 | 40.5±3.3 | ||
| Irvine et al. (1998) | Urine | 25 | 2-16 wk | Under limit of detection | - | |
| SEAD study | Urine | 128 | 0-12 mo | 11.8×/÷5.7 | 8.2×/÷5.0 | 2.4×/÷2.1 |
| Saliva | 120 | 0-12 mo | 0.7×/÷1.3 | 0.4×/÷1.4 | - | |
| Whole Blood | 30 | 0-12 mo | 14.2×/÷1.5 | 5.5×/÷1.5 | - | |
| Breastfed infants | ||||||
| Setchell et al. (1997) | Plasma | 7 | 4 mo | 2.8±0.7 | 1.5±0.1 | 0.5 |
| Venkataraman et al. (1992) | Urine | 5 | 2 mo | 1284±1089 | 697±653 | 2.9±2.9 |
| 5 | 4 mo | 161±108 | 179±80 | 59±42 | ||
| Franke et al. (2006) | Plasma | 11 | 2-4 wk | 5.2±3.5† | - | |
| SEAD study | Urine | 128 | 0-12 mo | 1.5×/÷4.8 | 1.5×/÷2.9 | 1.7×/÷1.2 |
| Saliva | 120 | 0-12 mo | 0.7×/÷1.3 | 0.4×/÷1.5 | - | |
| Whole Blood | 20 | 0-12 mo | 10.8×/÷2.7 | 5.3×/÷1.2 | - | |
*
Numbers of concentration are geometric mean±standard deviation or geometric mean×/÷geometric standard deviation
†
Total isoflavones concentration. Approximate conversion unit 3.8 ×10-3 moles/g