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. Author manuscript; available in PMC: 2009 Nov 4.
Published in final edited form as: Biochemistry. 2008 Oct 11;47(44):11647–11652. doi: 10.1021/bi801117t

Table 1. Hydrodynamic studies of sLDLR variants.

sLDLR Sample pH Concentration (mg/mL) Sedimentation Coefficient (S20,w) Axial Ratio (a/b)
Wild Type 7 0.41 5.3 3.9
Wild Type 5 0.36 6.1 1.3
H562K / H586K 7 0.11 5.5 3.0
H562K / H586K 5 0.23 5.4 3.5
H190 K / H562K / H586K 7 0.50 5.2 4.0
H190 K / H562K / H586K 5 0.25 5.1 4.3