Skip to main content
. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Adv Drug Deliv Rev. 2008 Jul 4;60(13-14):1527–1533. doi: 10.1016/j.addr.2008.06.002

Figure 4. MAO catalyzes the oxidative deamination of monoamines.

Figure 4

Monoamines are degraded by MAO to their correspondent aldehydes (R-CHO). This reaction produces also ammonia (NH3) and hydrogen peroxide (H2O2). Aldehydes are further oxidized by aldehyde dehydrogenase (ALDH) into carboxylic acids (R-COOH). NADH is a critical cofactor for this latter reaction.

HHS Vulnerability Disclosure