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. 2009 Feb;174(2):586–594. doi: 10.2353/ajpath.2009.080661

Figure 5.

Figure 5

Role of microglial LRP1 on cerebral ischemia-induced iNOS expression. A and B: Quantitative real-time RT-PCR analysis of iNOS expression in microglial cultures 3 hours after exposure to oxygen-glucose deprivation conditions (A) and brain extracts 24 hours after MCAO (B). NT, no treatment; +tPA, animals treated with tPA immediately after MCAO; Wt, wild-type mice; macLRP−, mice deficient in microglial LRP1. Error bars described SEM. n = 6. *P < 0.05 when compared with either macLRP− microglia (A) or with untreated (NT) tPA mice or untreated (NT) and treated (+tPA) macLRP mice (B).