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. 2009 Feb;174(2):701–711. doi: 10.2353/ajpath.2009.080606

Figure 4.

Figure 4

Analysis of renal function following BM transfusion. Urine protein/creatinine ratio (A) and serum creatinine concentration (B) measurements in the recipients of BMDC from db/m donor mice showed improvement in these parameters. In approximately 40% of animals, however, analysis of the urine protein/creatinine ratio (C) and serum creatinine level (D) showed deterioration in recipients of db/m or db/db BMDC infusion. Results of the analysis of pathology scores in this subgroup (E) showed increased level of tubular necrosis following BMDC infusion. The number of animals studied in (A, B, and C) = db/db n = 5, dbTxm n = 6, dbTxdb n = 6; and, (D and E) = db/db n = 3, dbTxm n = 4, dbTxdb n = 4.