Figure 1. Levofloxacin treatment rescues mice from intranasal SCHU S4 infection.
Balb/c mice were given 3 LD50 doses (103 CFU) of SCHU S4 via intra-nasal challenge, and then 24 hours later given 6.25 mg/kg body weight of levofloxacin via intra-peritoneal injections. As a control, mice were injected with PBS. Mice (10 mice per group) were given levofloxacin or PBS daily for thirteen days. Mice were monitored twice daily for up to two months.