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. Author manuscript; available in PMC: 2009 Dec 9.
Published in final edited form as: Vaccine. 2008 Oct 16;26(52):6874–6882. doi: 10.1016/j.vaccine.2008.09.077

Figure 2. Levofloxacin treatment given at 96 hours post-infection can rescue mice from intra-nasal SCHU S4 infection.

Figure 2

Balb/c mice were given approximately 3 LD50 doses (114 CFU) of SCHU S4 via intra-nasal challenge and then given levofloxacin (i. p., 40 mg/kg body weight) starting at one of the following times post-infection (Post): 48, 72, 96, or 120 hours. As a control, mice were injected with PBS. Mice (10 mice per group) were given levofloxacin or PBS daily for thirteen days. Mice were monitored twice daily for up to two months. Asterisk indicates statistically significant survival with p<0.0001