TABLE 3.

IC₅₀s of EA, FEA, CEA, and CQ on a human cell line and on P. falciparum strains with various degrees of CQ resistance

Inhibitor	IC50 (nM)
	P. falciparuma				Mammalian
	3D7	HB3	Dd2	K1	L6
EA	819 ± 142	1,325 ± 102	351 ± 55	970 ± 58	NDb
FEA	94 ± 32	138 ± 32	186 ± 33	95 ± 11	21 × 103
CEA	42 ± 5.5	72 ± 19	116 ± 12	86 ± 25	94 × 103
CQ	8.6 ± 0.4	16 ± 1.5	93 ± 8.7	163 ± 7.0	ND

^aResults are mean values and standard deviations. Data have been obtained from at least four independent experiments.

^bND, not determined.