TABLE 1.
Cell type | % Viability ± 1 SD in the presence of:
|
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PRO 2000 | D2S | DexS | Dex | DMSO | P-80 | Pcr-400 | |
HeLa | 103 ± 2 | 106 ± 3 | 103 ± 2 | 102 ± 5 | 99 ± 2 | 102 ± 5 | 99 ± 6 |
293T | 98 ± 3 | 95 ± 4 | 90 ± 5 | 93 ± 2 | 93 ± 2 | 99 ± 4 | 99 ± 2 |
293T-GFP | 104 ± 2 | 95 ± 3 | 84 ± 5 | 94 ± 3 | 104 ± 9 | 91 ± 9 | 109 ± 6 |
Ghost | 110 ± 11 | 102 ± 3 | 90 ± 9 | 98 ± 8 | 89 ± 5 | 104 ± 13 | 105 ± 0 |
Jurkat | 93 ± 6 | 98 ± 1 | 99 ± 1 | 100 ± 1 | 102 ± 2 | 104 ± 4 | 101 ± 4 |
CD4+ primary cells | 93 ± 2 | 106 ± 3 | 96 ± 5 | 108 ± 4 | 108 ± 4 | 95 ± 3 | 117 ± 15 |
C91PL | 106 ± 4 | 115 ± 10 | 93 ± 6 | 101 ± 6 | 96 ± 10 | 101 ± 3 | 101 ± 4 |
MT-2 | 100 ± 1 | 96 ± 7 | 95 ± 2 | 97 ± 3 | 103 ± 2 | 96 ± 3 | 104 ± 1 |
Inhibitors were added to cells at 100 μM for polyanions or 10 μM for peptides, and metabolic function after 3 days was measured by the MTT [3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide] assay.