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OMP profiles of E. coli Wi (A) and K. pneumoniae M (B) isolates expressing no CTX-M (lanes 1 and 2) or expressing CTX-M-2 (lanes 3 and 4), CTX-M-3 (lanes 5 and 6), CTX-M-9 (lanes 7 and 8), or CTX-M-15 (lanes 9 and 10). Lanes 1, 3, 5, 7, and 9 correspond to OMPs extracted from isolates cultured without ertapenem (ETP); lanes 2, 4, 6, 8, and 10 correspond to OMPs extracted after a single-step ertapenem selection (4× MIC for each).
