TABLE 2.

Discrimination criteria between PK models^a

Model	Mean value for ELV
	Alone				With ritonavir
	ECV	AIC	r2	Residual variability (%)	ECV	AIC	r2	Residual variability (%)
2 CPT; 1 ka; 1 lag time per dose	33.3	82.6	0.983	8.1	35.1	86.2	0.872	14.3
2 CPT; 1 ka; 2 lag time per dose; including alpha	28.4	76.9	0.991	7.6	29.1	78.1	0.937	12.6
2 CPT; 2kaand 2 lag time per dose; including alpha	25.2	72.3	0.992	6.2	26.9	75.9	0.932	11.3
3 CPT; 1 ka; 1 lag time per dose	30.7	81.5	0.984	8.3	33.9	87.7	0.810	15.9
3 CPT; 1 ka; 2 lag time per dose; including alpha	27.7	79.4	0.992	6.6	30.9	85.7	0.832	15.9
3 CPT; 2 ka and 2 lag time per dose; including alpha	25.6	77.1	0.991	5.7	28.3	82.6	0.912	11.5

^aBold type indicates the selected model. ELV, elvucitabine; CPT, compartment; ECV, estimator criteria value; AIC, Akaike information criterion.