Table 2a.

Baseline Characteristics Associated with Advanced Cancer Patient Having Versus Not Having Dependent Children

Measure	Unadjusted Analyses		Adjusted Analyses
	da or O.R. (95% CI)	p-value	da or O.R. (95% CI)	p-value
McGill Quality of Life Measures
Worriedc	0.10	0.01	0.09	0.006
Sadd	0.03	0.37	0.06	0.14
Terrifiede	0.08	0.03	0.03	0.43
Mental Health
Current Major Depressive Disorderb,f	1.68 (0.86-3.28)	0.13	1.92 (0.94-3.93)	0.07
Current Depression (Endicott criteria)b,g	1.88(0.93-3.82)	0.08	1.73(0.81-3.70)	0.16
Current Generalized Anxiety Disorderb,h	2.15(0.72-6.42)	0.17	2.09(0.68-6.41)	0.20
Current Panic Disorderb,i	4.94(2.05-11.92)	0.0004	5.41 (2.13-13.69)	0.0004
Current PTSDb,j	1.98(0.74-5.33)	0.17	1.05 (0.34-3.26)	0.94
Peacefulk	0.67 (0.44-1.02)	0.06	0.54 (0.33-0.86)	0.01
Terminal Illness Acknowledgementl	0.67 (0.42-1.04)	0.08	0.71 (0.42-1.19)	0.20
EOL Discussions
Discussion of EOL Care Wishesm	0.95(0.49-1.82)	0.87	0.98(0.59-1.61)	0.92
Discussion of Life Expectancyn	1.01 (0.65-1.57)	0.96	1.09 (0.54-2.20)	0.81
Treatment Preferences
Preference for chemotherapyo	0.86(0.58-1.29)	0.47	0.82(0.52-1.27)	0.37
Preference for antibioticsp	1.64(1.08-2.49)	0.02	1.49 (0.92-2.42)	0.11
Preference for feeding tubeq	1.62(1.05-2.48)	0.03	0.85(0.44-1.65)	0.64
Preference for respiratorr	1.17(0.74-1.84)	0.50	0.75(0.45-1.24)	0.26
Preference for any type of advanced	1.63(1.00-2.67)	0.05	0.94(0.54-1.63)	0.83
treatments
Extend Life Versus Relieve Paint	2.05(1.33-3.16)	0.001	1.77(1.07-2.93)	0.03
Advance Care Planning
DNRu	0.48 (0.30-0.75)	0.002	0.44 (0.26-0.75)	0.003
Living willv	0.39 (0.26-0.61)	<0.0001	0.49 (0.28-0.87)	0.01
Health Care Proxy and/or Durable	0.46 (0.30-0.70)	0.0003	0.21 (0.10-0.43)	<0.0001
Power of Attorneyw

Note: Bolded rows represent significant differences between patients with and without dependent children.

^a= mean differences expressed in standard deviations of baseline data

^b= Determined by a Structured Clinical Interview for the DSM (SCID) diagnosis; Confounders

^c= gender, symptom burden and Simmons

^d= NHOH, health insurance, gender, symptom burden and Parkland

^e= White Race, age, symptom burden, Catholic, Parkland and gender

^f= symptom burden and DFCI

^g= symptom burden and marriage

^h= symptom burden and age

ⁱ= gender and symptom burden

^j= age and symptom burden

^k= White Race, No Religion and Simmons

^l= Yale, Black Race, Hispanic Race, symptom burden and breast cancer

^m= Yale and Karnofsky

ⁿ= Simmons

^o= Charlson Index of Comorbidity and DFCI

^p= White Race, Age, Catholic and DFCI

^q= age, income, health insurance and Simmons

^r= age

^s= age, Hispanic Race and symptom burden

^t= White Race, age, Yale, Parkland and DFCI

^u= White Race, Yale and Karnofsky

^v= White Race, age, education, Black Race and NHOH

^w= White Race, education, marriage, income, Yale, lung cancer, Black Race, Simmons, NHOH