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. 2008 Nov;14(11):1722–1730. doi: 10.3201/eid1411.070467

Table 1. Difference in outpatient antimicrobial drug use DID in 21 European countries, 2004, and changes in use, 2000–2004*†.

Substance class (ATC category) Antimicrobial use, DIDs, 2004
Changes in antimicrobial drug use, 2000–2004
Maximum (country) Minimum (country) fd >15% increase >15% decrease
Total use (J01) 33.4(GR) 9.7 (NL) 3.4 HU, DK, GR, IE BG, CZ, DE, FR
Penicillins (J01C) 12.8 (FR) 3.4 (DE) 3.8 HU, DK CZ, FR, DE, SK
Cephalosporins, monobactams, carbapenems (J01D) 7.2 (GR) 0.05 (NL) >100 SI BE, BG, CZ, FR, IS NL, ES, SE
Macrolides, lincosamines, streptogramins (J01F) 9.9 (GR) 0.8 (BG) 12.4 BG, HR, GR, IE, NL BE, FR, DE, LU, ES
Fluoroquinolones (J01MA) 3.04 (PT) 0.28 (DK) 10.9 AT, BG, CZ, DK, FI, DE, HU, IE, LU, UK SI

*DID, defined daily dose/1,000 inhabitants; ATC, Anatomic Therapeutic Chemical classification; fd, factor difference.
†Country designations: AT, Austria; BE, Belgium; BG, Bulgaria; CZ, Czech Republic; DE, Germany; DK, Denmark; ES, Spain; FI, Finland; FR, France; GR, Greece; HR, Croatia; HU, Hungary; IE, Ireland; LU, Luxembourg; NL, the Netherlands; PT, Portugal; SE, Sweden; SI, Slovenia; SK, Slovakia; UK, United Kingdom.