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Collected tissue weights (mg) at the termination of the experiment. ▪, MC4R KO sedentary group; □, MC4R KO RW group, ▩, WT littermate sedentary group; ▥, WT RW group. Values are averages ± se; n = 10–12 mice/group. ***P < 0.001; two-way ANOVA with Bonferroni post hoc tests.
