TABLE 1.
Physiological variables in PPARα−/− and PPARα+/+ mice in the fed and fasted states
| Variable | PPARα+/+
|
PPARα−/−
|
||
|---|---|---|---|---|
| Fed | Fasted | Fed | Fasted | |
| Age (wk) | 15.3 ± 0.6 | 15.1 ± 0.6 | 16.2 ± 0.1 | 16.2 ± 0.1 |
| Weight (g) | 31.7 ± 1.2 | 25.2 ± 0.8 | 28.2 ± 0.8 | 26.3 ± 0.8 |
| Glucose (mg/dl) | 141.1 ± 5.9 | 75.8 ± 2.4 | 133.6 ± 2.4 | 56.7 ± 2.1 |
| Insulin (ng/ml) | 0.593 ± 0.222 | 0.193 ± 0.075 | 0.412 ± 0.061 | 0.362 ± 0.059 |
| Insulin:glucose ratio | 4.2 ± 1.6 | 2.2 ± 0.9 | 3.1 ± 0.5 | 6.4 ± 1.0 |
| NEFA (mM) | 0.231 ± 0.032 | 0.469 ± 0.040 | 0.185 ± 0.022 | 1.145 ± 0.049 |
| Total ketones (μM) | 266.4 ± 19.2 | 1514.0 ± 111.0 | 225.4 ± 29.4 | 564.7 ± 35.1 |
Values are expressed as means ± se.