Table 1.

Rectal cancer pooled analysis: Effect of NT stage on survival and relapse.

	Overall survival*			Disease-free survival*			Local recurrence†		Distant metastasis†
Stage	No. pts	5-yr(%)	P value	No. pts	5-yr(%)	P value	5-yr(%)	P value	5-y r(%)	P value
N0T3	668	74	.046	664	66	.05†	8	.04	19	.04
T4	95	65		95	54		15		28
N1T1-2	225	81	< .001	225	74	< .001	6	.002	15	< .001
T3	544	61		536	50		11		34
T4	59	33		59	30		22		39
N2T1-2	180	69	< .001	180	62	< .001	8	.14	26	< .001
T3	663	48		659	39		15		45
T4	84	38		84	30		19		50

Modified from Gunderson et al.¹¹

^*Unadjusted Kaplan-Meier survival estimates

^†Cumulative incidence rates