Table 7.
Local relapse by radial margin, TME alone vs. RT plus TME: Dutch phase III trial.
| TME alone
|
Preop RT + TME
|
||||
|---|---|---|---|---|---|
| Local relapse
|
Local relapse
|
||||
| Radial margin | No. pts | 2-yr (%) | No. pts | 2-yr (%) | P Value |
| ≥ 1 cm* | 264* | 3.3 | 286* | 0.0 | .0002 |
| > 2 mm | 483 | 5.8 | 504 | 0.9 | < .0001 |
| > 1 to ≤ 2 mm | 53 | 14.9 | 47 | 0.0 | .02 |
| ≤ 1 mm | 120 | 16.4 | 107 | 9.3 | .08 |
| Total | 656 | 8.4 | 658 | 2.1 | < .0001 |
Modified from Marijnen et al30
*
Subset of patients with > 2 mm radial margin
Abbreviations: RT = radiotherapy; TME = total mesorectal excision.