Table 1.
Cost data* for radiotherapy, chemotherapy, and toxicity management.
| Sensitivity analysis range
|
|||||||
|---|---|---|---|---|---|---|---|
| Description | HCPCS | Unit cost | Quantity or % | Base-case total cost | Low | High | Reference |
| Radiotherapy | |||||||
| Initial consultation | 99245 | $213.93 | 1 | $213.93 | $149.75 | $342.29 | 24 |
| Complex treatment plan | 77263 | $153.97 | 1 | $153.97 | $137.57 | $183.67 | 23 |
| Complex simulation | 77290 | $388.66 | 2 | $777.32 | $571.72 | $1,144.60 | 23 |
| 3D simulation | 77295 | $1,114.21 | 1 | $1,114.21 | $805.68 | $1,607.64 | 23 |
| Blocks/moulds | 77334 | $179.60 | 5 | $898.00 | $677.75 | $1,258.65 | 23 |
| Basic dosimetry calculation | 77300 | $79.32 | 4 | $317.28 | $242.44 | $440.12 | 23 |
| Continuing medical physics consults | 77336 | $99.71 | 5 | $498.55 | $341.55 | $757.65 | 23 |
| Radiation treatment management | 77427 | $175.52 | 5 | $877.60 | $791.60 | $1,038.75 | 23 |
| Concurrent chemotherapy | 77470 | $447.16 | 1 | $447.16 | $325.75 | $640.31 | 23 |
| Weekly CBC count | 85025 | $14.68 | 5 | $73.40 | $51.38 | $117.44 | 25 |
| Weekly port films | 77417 | $21.26 | 5 | $106.30 | $72.15 | $160.10 | 23 |
| Radiation treatment delivery | 77414 | $140.84 | 25 | $3,521.00 | $2,468.75 | $5,469.00 | 23 |
| Total radiotherapy costs: | $8,998.72 | $6,636.09 | $13,160.22 | ||||
| Chemotherapy | |||||||
| Initial consultation | 99245 | $231.10 | 1 | $231.10 | $161.77 | $369.75 | 24 |
| Management office visits | 99213 | $53.09 | 5 | $265.46 | $185.82 | $424.73 | 24 |
| 5-Fluorouracil 500-mg vial (x2) | J9190 | $1.66 | 44 | $73.04 | $51.13 | $116.86 | 28 |
| Initial CTX administration | 96409 | $117.12 | 22 | $2,576.64 | $1,874.62 | $3,938.66 | 23 |
| Leucovorin 50-mg vial | J0640 | $1.03 | 22 | $22.66 | $15.86 | $36.26 | 28 |
| Additional CTX administration | 96411 | $67.48 | 22 | $1,484.56 | $1,083.72 | $2,227.72 | 23 |
| CBC count | 85025 | $14.68 | 17 | $249.56 | $174.69 | $399.30 | 25 |
| Complete metabolic panel | 80053 | $19.96 | 2 | $39.92 | $27.94 | $63.87 | 25 |
| Total chemotherapy costs: | $4,942.94 | $3,460.05 | $7,908.70 | ||||
| Toxicity management | |||||||
| Neutropenia | |||||||
| Neutropenic hospitalizations | $13,224.12 | 2.98% | $394.08 | $197.04 | $1,182.24 | 26 | |
| Outpatient neutropenia management | $1,544.01 | 51% | $787.75 | $393.88 | $2,363.26 | 27 | |
| Filgrastim | $3,978.87 | 51% | $2,030.02 | $1,015.01 | $6,090.06 | 28 | |
| Nausea/vomiting | |||||||
| Management of CINV × 5 cycles | $2,976.09 | 100 | $2,976.09 | $1,488.04 | $8,928.27 | 29 | |
| Total toxicity costs: | $6,187.94 | $3,094.00 | $18,564.00 | ||||
*
All costs converted to 2007 US dollars.22
Abbreviations: HCPCS = Healthcare Common Procedure Coding System; CBC = complete blood cell; CTX = chemotherapy; CINV = chemotherapy-induced nausea & vomiting.