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. 2008 Sep 4;150(1):385–395. doi: 10.1210/en.2008-0674

Figure 1.

Figure 1

Chemical structures, AR binding affinity, and in vitro transcriptional activation of C-6 and S-23. AR binding affinity was determined using a radioligand competitive assay. The ability of compound of interest to induce AR-mediated transcriptional activation was determined using a cotransfection assay in CV-1 cells. The transcriptional activity induced by each compound at a concentration of 10 nm was reported as the percentage of that observed for 1 nm DHT. Each value represents the mean ± sd of three replicates. *, Data were reported by Chen et al. (13).